CPHI in Barcelona: Oncology projects ranging from medical.

Oct 20, 2023 | Pharma / Biotech

Connectem Barcelona

At CPhI Karim will be very keen to present interesting oncology projects ranging from medical nutrition to new anticancer drugs in preclinical stage.

Of special interest are anticancer compounds that target cancer stem cells.

What are the cancer stem cell?

These cells have the ability to self-renew and differentiate into various cell types within the tumor.

Cancer stem cells contribute to tumor heterogeneity, meaning that tumors are composed of different cell types. This heterogeneity can affect how tumors respond to treatment and may contribute to the recurrence of cancer.

Cancer stem cells are thought to be more resistant to conventional cancer treatments, such as chemotherapy and radiation. This resistance may be one reason for treatment failure and cancer recurrence.

Understanding and targeting cancer stem cells is an active area of research in oncology. Scientists are exploring ways to develop therapies that specifically target these cells to improve treatment outcomes and reduce the likelihood of cancer recurrence. The identification and characterization of cancer stem cells vary depending on the type of cancer, and research in this field continues to evolve.

Here are some key characteristics and features of cancer stem cells:

Self-Renewal:

Cancer stem cells can divide and produce both identical stem cells (self- renewal) and differentiated cells that make up the bulk of the tumor.

Tumor Initiation:

These cells are thought to play a crucial role in the initiation of tumors, as they have the ability to generate new tumors when transplanted into experimental models.

Resistance to Treatment:

Cancer stem cells are believed to be more resistant to conventional cancer treatments, such as chemotherapy and radiation therapy. This resistance may contribute to treatment failure and relapse.

Heterogeneity:

Tumors are composed of a heterogeneous population of cells, and cancer stem cells contribute to this diversity. They have the potential to give rise to various cell types within the tumor.

Developing therapies that specifically target these cells could potentially improve treatment
outcomes and reduce the risk of cancer recurrence.